Julian Knight : Challenges and opportunities of genomics in sepsis
In this talk I will describe how recent advances in genomics can be applied to sepsis, from human genetics to multi-omics. I will present work advancing our understanding of heterogeneity in the host response to infection that has been well recognised in sepsis, advancing opportunities for personalised care. In the talk I will highlight current challenges in application of genomic approaches and their analysis together with opportunities to maximise the informativeness of such data.
Julian Knight is a Professor of Genomic Medicine at the University of Oxford & Honorary Consultant Physician at the Oxford University Hospitals NHS Trust (UK). He is a Principal Investigator at the Centre for Human Genetics, leading work investigating the genomics of immunity and how this can determine our individual response to infections such as sepsis. He is clinically active in internal medicine and a Fellow of the Academy of Medical Sciences. His work is focused on advancing genomic medicine into the clinic, combining an active research programme with leadership in education and training.